David A. Sinclair Quotes

Who is David A. Sinclair?

David Andrew Sinclair is an Australian biologist and professor of genetics. He is known for his research on aging and epigenetics.

Sinclair wrote the book 'Lifespan: Why We Age – and Why We Don’t Have To'.

Born June 26, 1969

Books by David A. Sinclair


Best 27 Quotes by David A. Sinclair

“I actually think it will be possible one day to be immortal.”

David A. Sinclair

“Scientists don't like to be called salesmen.”

David A. Sinclair

Lifespan Quotes

“A few years ago, researchers noticed a curious phenomenon: people taking metformin were living notably healthier lives — independent, it seemed, of its effect on diabetes.”

David A. Sinclair
Lifespan

“Aging, quite simply, is a loss of information.”

David A. Sinclair
Lifespan

“And that’s the world’s biggest problem: the future is seen as someone else’s concern.”

David A. Sinclair
Lifespan

“As a species, we are living much longer than ever. But not much better. Not at all. Over the past century we have gained additional years, but not additional life — not life worth living anyway.”

David A. Sinclair
Lifespan

“As cloning beautifully proves, our cells retain their youthful digital information even when we are old. To become young again, we just need to find some polish to remove the scratches.”

David A. Sinclair
Lifespan

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“Doctors will prescribe medicines for a particular disease but, as a side effect, those medications will work to prevent dozens of others.”

David A. Sinclair
Lifespan

“Exposing your body to less-than-comfortable temperatures is another very effective way to turn on your longevity genes.”

David A. Sinclair
Lifespan

“I believe that aging is a disease. I believe it is treatable. I believe we can treat it within our lifetimes. And in doing so, I believe, everything we know about human health will be fundamentally changed.”

David A. Sinclair
Lifespan

“In my mind, there are few sins so egregious as extending life without health. This is important. It does not matter if we can extend lifespans if we cannot extend healthspans to an equal extent. And so if we’re going to do the former, we have an absolute moral obligation to do the latter.”

David A. Sinclair
Lifespan

“Only 20 percent of our longevity is genetically determined. The rest is what we do, how we live our lives and increasingly the molecules that we take. It's not the loss of our DNA that causes aging, it's the problems in reading the information, the epigenetic noise.”

David A. Sinclair
Lifespan

“Separating aging from disease obfuscates a truth about how we reach the ends of our lives: though it’s certainly important to know why someone fell from a cliff, it’s equally important to know what brought that person to the precipice in the first place. Aging brings us to the precipice. Give any of us 100 years or so, and it brings us all there.”

David A. Sinclair
Lifespan

“Simply keeping people alive — decades after their lives have become defined by pain, disease, frailty, and immobility — is no virtue.”

David A. Sinclair
Lifespan

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“Thanks to an increasingly sedentary lifestyle and the abundance of sugars and carbohydrates on every supermarket shelf around the globe, high blood sugar is causing the premature deaths of 3.8 million people a year.”

David A. Sinclair
Lifespan

“The longevity genes I work on are called 'sirtuins', named after the yeast SIR2 gene, the first one to be discovered. There are seven sirtuins in mammals, SIRT1 to SIRT7, and they are made by almost every cell in the body.”

David A. Sinclair
Lifespan

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“The tastiest strawberries have been stressed by periods of limited water intake.”

David A. Sinclair
Lifespan

“The way to make a worm live longer is probably quite different from making a human live longer.”

David A. Sinclair
Lifespan

“There are plenty of stressors that will activate longevity genes without damaging the cell, including certain types of exercise, intermittent fasting, low-protein diets, and exposure to hot and cold temperatures.”

David A. Sinclair
Lifespan

“There is nothing more dangerous to us than age. Yet we have conceded its power over us. And we have turned our fight for better health in other directions.”

David A. Sinclair
Lifespan

“There isn’t much debate on the downsides of consumption of animal protein. Study after study has demonstrated that heavily animal-based diets are associated with high cardiovascular mortality and cancer risk.”

David A. Sinclair
Lifespan

“Though smoking increases the risk of getting cancer fivefold, being 50 years old increases your cancer risk a hundredfold.”

David A. Sinclair
Lifespan

“Unfortunately, because aging is so common and natural, we tend to think of it as destiny or something we should accept.”

David A. Sinclair
Lifespan

“We know more about the health of our cars than we know about our own health. That’s farcical. And it’s about to change.”

David A. Sinclair
Lifespan

“We once thought of cancer as an incurable disease; then we started treating it.”

David A. Sinclair
Lifespan

“Why would we choose to focus on problems that impact small groups of people if we could address the problem that impacts everyone – especially if, in doing so, we could significantly impact all those other, smaller problems?”

David A. Sinclair
Lifespan

“Youth → broken DNA → genome instability → disruption of DNA packaging and gene regulation (the epigenome) → loss of cell identity → cellular senescence → disease → death.”

David A. Sinclair
Lifespan